An SEIR model of influenza A virus infection and reinfection within a farrow-to-finish swine farm.
Identifieur interne : 000068 ( Main/Exploration ); précédent : 000067; suivant : 000069An SEIR model of influenza A virus infection and reinfection within a farrow-to-finish swine farm.
Auteurs : Fatima Etbaigha ; Allan R Willms ; Zvonimir PoljakSource :
- PloS one [ 1932-6203 ] ; 2018.
Descripteurs français
- KwdFr :
- MESH :
- médecine vétérinaire : Infections à Orthomyxoviridae, Vaccination.
- pathogénicité : Virus de la grippe A.
- virologie : Maladies des porcs.
- épidémiologie : Infections à Orthomyxoviridae, Ontario.
- Animaux, Fermes, Modèles théoriques, Suidae, Élevage.
English descriptors
- KwdEn :
- MESH :
- geographic , epidemiology : Ontario.
- epidemiology : Orthomyxoviridae Infections.
- pathogenicity : Influenza A virus.
- veterinary : Orthomyxoviridae Infections, Vaccination.
- virology : Swine Diseases.
- Animal Husbandry, Animals, Farms, Models, Theoretical, Swine.
Abstract
Influenza A virus (IAV) in swine is a pathogen that causes a threat to the health as well as to the production of swine. Moreover, swine can spread this virus to other species including humans. The virus persists in different types of swine farms as evident in a number of studies. The core objectives of this study are (i) to analyze the dynamics of influenza infection of a farrow-to-finish swine farm, (ii) to explore the reinfection at the farm level, and finally (iii) to examine the effectiveness of two control strategies: vaccination and reduction of indirect contact. The analyses are conducted using a deterministic Susceptible-Exposed-Infectious-Recovered (SEIR) model. Simulation results show that the disease is maintained in gilts and piglets because of new susceptible pigs entering the population on a weekly basis. A sensitivity analysis shows that the results are not sensitive to variation in the parameters. The results of the reinfection simulation indicate that the virus persists in the entire farm. The control strategies studied in this work are not successful in eliminating the virus within the farm.
DOI: 10.1371/journal.pone.0202493
PubMed: 30248106
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">An SEIR model of influenza A virus infection and reinfection within a farrow-to-finish swine farm.</title><author><name sortKey="Etbaigha, Fatima" sort="Etbaigha, Fatima" uniqKey="Etbaigha F" first="Fatima" last="Etbaigha">Fatima Etbaigha</name><affiliation><nlm:affiliation>Department of Mathematics and Statistics, University of Guelph, Guelph, Ontario N1G 2W1 Canada.</nlm:affiliation><wicri:noCountry code="subField">Ontario N1G 2W1 Canada</wicri:noCountry></affiliation></author><author><name sortKey="R Willms, Allan" sort="R Willms, Allan" uniqKey="R Willms A" first="Allan" last="R Willms">Allan R Willms</name><affiliation><nlm:affiliation>Department of Mathematics and Statistics, University of Guelph, Guelph, Ontario N1G 2W1 Canada.</nlm:affiliation><wicri:noCountry code="subField">Ontario N1G 2W1 Canada</wicri:noCountry></affiliation></author><author><name sortKey="Poljak, Zvonimir" sort="Poljak, Zvonimir" uniqKey="Poljak Z" first="Zvonimir" last="Poljak">Zvonimir Poljak</name><affiliation><nlm:affiliation>Department of Population Medicine, University of Guelph, Guelph, Ontario N1G 2W1 Canada.</nlm:affiliation><wicri:noCountry code="subField">Ontario N1G 2W1 Canada</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2018">2018</date><idno type="RBID">pubmed:30248106</idno><idno type="pmid">30248106</idno><idno type="doi">10.1371/journal.pone.0202493</idno><idno type="wicri:Area/Main/Corpus">000035</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000035</idno><idno type="wicri:Area/Main/Curation">000035</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000035</idno><idno type="wicri:Area/Main/Exploration">000035</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">An SEIR model of influenza A virus infection and reinfection within a farrow-to-finish swine farm.</title><author><name sortKey="Etbaigha, Fatima" sort="Etbaigha, Fatima" uniqKey="Etbaigha F" first="Fatima" last="Etbaigha">Fatima Etbaigha</name><affiliation><nlm:affiliation>Department of Mathematics and Statistics, University of Guelph, Guelph, Ontario N1G 2W1 Canada.</nlm:affiliation><wicri:noCountry code="subField">Ontario N1G 2W1 Canada</wicri:noCountry></affiliation></author><author><name sortKey="R Willms, Allan" sort="R Willms, Allan" uniqKey="R Willms A" first="Allan" last="R Willms">Allan R Willms</name><affiliation><nlm:affiliation>Department of Mathematics and Statistics, University of Guelph, Guelph, Ontario N1G 2W1 Canada.</nlm:affiliation><wicri:noCountry code="subField">Ontario N1G 2W1 Canada</wicri:noCountry></affiliation></author><author><name sortKey="Poljak, Zvonimir" sort="Poljak, Zvonimir" uniqKey="Poljak Z" first="Zvonimir" last="Poljak">Zvonimir Poljak</name><affiliation><nlm:affiliation>Department of Population Medicine, University of Guelph, Guelph, Ontario N1G 2W1 Canada.</nlm:affiliation><wicri:noCountry code="subField">Ontario N1G 2W1 Canada</wicri:noCountry></affiliation></author></analytic><series><title level="j">PloS one</title><idno type="eISSN">1932-6203</idno><imprint><date when="2018" type="published">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animal Husbandry</term><term>Animals</term><term>Farms</term><term>Influenza A virus (pathogenicity)</term><term>Models, Theoretical</term><term>Ontario (epidemiology)</term><term>Orthomyxoviridae Infections (epidemiology)</term><term>Orthomyxoviridae Infections (veterinary)</term><term>Swine</term><term>Swine Diseases (virology)</term><term>Vaccination (veterinary)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Fermes</term><term>Infections à Orthomyxoviridae (médecine vétérinaire)</term><term>Infections à Orthomyxoviridae (épidémiologie)</term><term>Maladies des porcs (virologie)</term><term>Modèles théoriques</term><term>Ontario (épidémiologie)</term><term>Suidae</term><term>Vaccination (médecine vétérinaire)</term><term>Virus de la grippe A (pathogénicité)</term><term>Élevage</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Ontario</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Orthomyxoviridae Infections</term></keywords><keywords scheme="MESH" qualifier="médecine vétérinaire" xml:lang="fr"><term>Infections à Orthomyxoviridae</term><term>Vaccination</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Influenza A virus</term></keywords><keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="veterinary" xml:lang="en"><term>Orthomyxoviridae Infections</term><term>Vaccination</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Maladies des porcs</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Swine Diseases</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à Orthomyxoviridae</term><term>Ontario</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animal Husbandry</term><term>Animals</term><term>Farms</term><term>Models, Theoretical</term><term>Swine</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Fermes</term><term>Modèles théoriques</term><term>Suidae</term><term>Élevage</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Influenza A virus (IAV) in swine is a pathogen that causes a threat to the health as well as to the production of swine. Moreover, swine can spread this virus to other species including humans. The virus persists in different types of swine farms as evident in a number of studies. The core objectives of this study are (i) to analyze the dynamics of influenza infection of a farrow-to-finish swine farm, (ii) to explore the reinfection at the farm level, and finally (iii) to examine the effectiveness of two control strategies: vaccination and reduction of indirect contact. The analyses are conducted using a deterministic Susceptible-Exposed-Infectious-Recovered (SEIR) model. Simulation results show that the disease is maintained in gilts and piglets because of new susceptible pigs entering the population on a weekly basis. A sensitivity analysis shows that the results are not sensitive to variation in the parameters. The results of the reinfection simulation indicate that the virus persists in the entire farm. The control strategies studied in this work are not successful in eliminating the virus within the farm.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">30248106</PMID><DateCompleted><Year>2019</Year><Month>02</Month><Day>19</Day></DateCompleted><DateRevised><Year>2020</Year><Month>03</Month><Day>19</Day></DateRevised><Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">1932-6203</ISSN><JournalIssue CitedMedium="Internet"><Volume>13</Volume><Issue>9</Issue><PubDate><Year>2018</Year></PubDate></JournalIssue><Title>PloS one</Title><ISOAbbreviation>PLoS ONE</ISOAbbreviation></Journal><ArticleTitle>An SEIR model of influenza A virus infection and reinfection within a farrow-to-finish swine farm.</ArticleTitle><Pagination><MedlinePgn>e0202493</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1371/journal.pone.0202493</ELocationID><Abstract><AbstractText>Influenza A virus (IAV) in swine is a pathogen that causes a threat to the health as well as to the production of swine. Moreover, swine can spread this virus to other species including humans. The virus persists in different types of swine farms as evident in a number of studies. The core objectives of this study are (i) to analyze the dynamics of influenza infection of a farrow-to-finish swine farm, (ii) to explore the reinfection at the farm level, and finally (iii) to examine the effectiveness of two control strategies: vaccination and reduction of indirect contact. The analyses are conducted using a deterministic Susceptible-Exposed-Infectious-Recovered (SEIR) model. Simulation results show that the disease is maintained in gilts and piglets because of new susceptible pigs entering the population on a weekly basis. A sensitivity analysis shows that the results are not sensitive to variation in the parameters. The results of the reinfection simulation indicate that the virus persists in the entire farm. The control strategies studied in this work are not successful in eliminating the virus within the farm.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Etbaigha</LastName><ForeName>Fatima</ForeName><Initials>F</Initials><Identifier Source="ORCID">0000-0001-5044-074X</Identifier><AffiliationInfo><Affiliation>Department of Mathematics and Statistics, University of Guelph, Guelph, Ontario N1G 2W1 Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>R Willms</LastName><ForeName>Allan</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Mathematics and Statistics, University of Guelph, Guelph, Ontario N1G 2W1 Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Poljak</LastName><ForeName>Zvonimir</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Department of Population Medicine, University of Guelph, Guelph, Ontario N1G 2W1 Canada.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2018</Year><Month>09</Month><Day>24</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>PLoS One</MedlineTA><NlmUniqueID>101285081</NlmUniqueID><ISSNLinking>1932-6203</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000822" MajorTopicYN="N">Animal Husbandry</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000072480" MajorTopicYN="N">Farms</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009980" MajorTopicYN="N">Influenza A virus</DescriptorName><QualifierName UI="Q000472" MajorTopicYN="Y">pathogenicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008962" MajorTopicYN="N">Models, Theoretical</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009864" MajorTopicYN="N" Type="Geographic">Ontario</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009976" MajorTopicYN="N">Orthomyxoviridae Infections</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName><QualifierName UI="Q000662" MajorTopicYN="Y">veterinary</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013552" MajorTopicYN="N">Swine</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013553" MajorTopicYN="N">Swine Diseases</DescriptorName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014611" MajorTopicYN="N">Vaccination</DescriptorName><QualifierName UI="Q000662" MajorTopicYN="N">veterinary</QualifierName></MeshHeading></MeshHeadingList><CoiStatement>The authors have declared that no competing interests exist.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>09</Month><Day>30</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2018</Year><Month>08</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2018</Year><Month>9</Month><Day>25</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2018</Year><Month>9</Month><Day>25</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2019</Year><Month>3</Month><Day>21</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">30248106</ArticleId><ArticleId IdType="doi">10.1371/journal.pone.0202493</ArticleId><ArticleId IdType="pii">PONE-D-17-35388</ArticleId><ArticleId IdType="pmc">PMC6152865</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Am J Vet Res. 1990 Jan;51(1):156-64</Citation><ArticleIdList><ArticleId IdType="pubmed">2301815</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2014 Aug 27;9(8):e106177</Citation><ArticleIdList><ArticleId IdType="pubmed">25162536</ArticleId></ArticleIdList></Reference><Reference><Citation>Vet Q. 2006 Jun;28(2):46-53</Citation><ArticleIdList><ArticleId IdType="pubmed">16841566</ArticleId></ArticleIdList></Reference><Reference><Citation>Vet Microbiol. 2000 May 22;74(1-2):29-46</Citation><ArticleIdList><ArticleId IdType="pubmed">10799776</ArticleId></ArticleIdList></Reference><Reference><Citation>Vet Immunol Immunopathol. 2011 Jul 15;142(1-2):81-6</Citation><ArticleIdList><ArticleId IdType="pubmed">21501880</ArticleId></ArticleIdList></Reference><Reference><Citation>Virus Res. 2002 May 10;85(2):199-210</Citation><ArticleIdList><ArticleId IdType="pubmed">12034486</ArticleId></ArticleIdList></Reference><Reference><Citation>Transbound Emerg Dis. 2012 Mar;59 Suppl 1:68-84</Citation><ArticleIdList><ArticleId IdType="pubmed">22226050</ArticleId></ArticleIdList></Reference><Reference><Citation>Zoonoses Public Health. 2013 Sep;60(6):383-411</Citation><ArticleIdList><ArticleId IdType="pubmed">22937896</ArticleId></ArticleIdList></Reference><Reference><Citation>Vet Microbiol. 2003 Feb 25;91(4):295-308</Citation><ArticleIdList><ArticleId IdType="pubmed">12477644</ArticleId></ArticleIdList></Reference><Reference><Citation>Vet Res. 2011 Dec 20;42:120</Citation><ArticleIdList><ArticleId IdType="pubmed">22185601</ArticleId></ArticleIdList></Reference><Reference><Citation>Can J Vet Res. 2008 Jan;72(1):7-17</Citation><ArticleIdList><ArticleId IdType="pubmed">18214156</ArticleId></ArticleIdList></Reference><Reference><Citation>Vaccine. 2013 Jan 7;31(3):500-5</Citation><ArticleIdList><ArticleId IdType="pubmed">23174202</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2016 Sep 23;11(9):e0163672</Citation><ArticleIdList><ArticleId IdType="pubmed">27662592</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Curr. 2015 Apr 13;7:</Citation><ArticleIdList><ArticleId IdType="pubmed">25932349</ArticleId></ArticleIdList></Reference><Reference><Citation>J R Soc Interface. 2016 Jun;13(119):</Citation><ArticleIdList><ArticleId IdType="pubmed">27358277</ArticleId></ArticleIdList></Reference><Reference><Citation>Vet Immunol Immunopathol. 2003 Mar 20;92(1-2):23-35</Citation><ArticleIdList><ArticleId IdType="pubmed">12628761</ArticleId></ArticleIdList></Reference><Reference><Citation>Prev Vet Med. 2016 Nov 1;134:58-68</Citation><ArticleIdList><ArticleId IdType="pubmed">27836046</ArticleId></ArticleIdList></Reference><Reference><Citation>Prev Vet Med. 2010 Mar 1;93(4):248-57</Citation><ArticleIdList><ArticleId IdType="pubmed">20004990</ArticleId></ArticleIdList></Reference><Reference><Citation>J Food Prot. 2004 Nov;67(11):2403-9</Citation><ArticleIdList><ArticleId IdType="pubmed">15553620</ArticleId></ArticleIdList></Reference><Reference><Citation>Prev Vet Med. 2017 Mar 1;138:55-69</Citation><ArticleIdList><ArticleId IdType="pubmed">28237236</ArticleId></ArticleIdList></Reference><Reference><Citation>Adv Virus Res. 2008;72:127-54</Citation><ArticleIdList><ArticleId IdType="pubmed">19081490</ArticleId></ArticleIdList></Reference><Reference><Citation>Hum Exp Toxicol. 2002 Sep-Oct;21(9-10):533-6</Citation><ArticleIdList><ArticleId IdType="pubmed">12458912</ArticleId></ArticleIdList></Reference><Reference><Citation>Vaccine. 2001 Aug 14;19(31):4479-86</Citation><ArticleIdList><ArticleId IdType="pubmed">11483274</ArticleId></ArticleIdList></Reference><Reference><Citation>Virol J. 2011 Dec 14;8:537</Citation><ArticleIdList><ArticleId IdType="pubmed">22166074</ArticleId></ArticleIdList></Reference><Reference><Citation>Arch Virol. 2000;145(7):1399-419</Citation><ArticleIdList><ArticleId IdType="pubmed">10963345</ArticleId></ArticleIdList></Reference><Reference><Citation>Influenza Other Respir Viruses. 2008 May;2(3):99-105</Citation><ArticleIdList><ArticleId IdType="pubmed">19453469</ArticleId></ArticleIdList></Reference><Reference><Citation>J R Soc Interface. 2012 Jan 7;9(66):89-101</Citation><ArticleIdList><ArticleId IdType="pubmed">21632614</ArticleId></ArticleIdList></Reference><Reference><Citation>Prev Vet Med. 2008 Jan 1;83(1):24-40</Citation><ArticleIdList><ArticleId IdType="pubmed">17604859</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list></list><tree><noCountry><name sortKey="Etbaigha, Fatima" sort="Etbaigha, Fatima" uniqKey="Etbaigha F" first="Fatima" last="Etbaigha">Fatima Etbaigha</name><name sortKey="Poljak, Zvonimir" sort="Poljak, Zvonimir" uniqKey="Poljak Z" first="Zvonimir" last="Poljak">Zvonimir Poljak</name><name sortKey="R Willms, Allan" sort="R Willms, Allan" uniqKey="R Willms A" first="Allan" last="R Willms">Allan R Willms</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/GrippeCanadaV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000068 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000068 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= GrippeCanadaV3
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:30248106
|texte= An SEIR model of influenza A virus infection and reinfection within a farrow-to-finish swine farm.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:30248106" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a GrippeCanadaV3
| This area was generated with Dilib version V0.6.35. |  |